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Minocycline belongs to a group of antibiotics called tetracyclines. The acne treatments doxycycline and tetracycline also belong to this group. Minocycline is also is used to treat respiratory and urinary tract infections as well as some sexually transmitted infections.

Shaughnessy, K.K.; Bouchard, S.M.; Mohr, M.R.; Herre, J.M.; Salkey, K.S. Minocycline-induced drug reaction with eosinophilia and systemic symptoms syndrome with persistent myocarditis. The cause of rosacea is unknown but it is suspected to be multifactorial with genetic factors and environmental components playing a role. A damaged skin barrier may also play a role in initiating or augmenting rosacea . In fact, those with papulopustular rosacea have skin barrier damage similar to those with atopic dermatitis . An intact skin barrier maintains homeostasis by protecting the body from microbes and preserving a waterproof shell .

Minocycline may increase or decrease the effects of other medications. For example, minocycline and other tetracyclines may potentiate the hypoprothrombinemic activity of warfarin and other anticoagulants often administered for life. The dosage of the anticoagulant must be adjusted when taking minocycline to avoid hemorrhages. Similarly, minocycline increases the serum levels of digoxin, which is used to treat atrial fibrillation and other heart conditions. The interaction of minocycline with insulin should be carefully considered. The FDA places warnings on some tetracyclines to indicate that their administration may reduce the efficiency of oral contraceptives .

Niacinminocycline will decrease the level or effect of niacin by altering intestinal flora. Colestipolcolestipol decreases levels of minocycline by inhibition of GI absorption. Biotinminocycline will decrease the level or effect of biotin by altering intestinal flora.

Minocycline also kills certain bacteria on the skin that can cause acne. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, saint louis university philosophy or street drugs can affect the action of many medications, you should let your prescriber know if you use them. These factors may affect how you should use this medication.

Minocycline-induced lupus is another serious adverse effect that may be caused by systemic administration of minocycline and other drugs. MIL shows clinical symptoms like those of SLE, being characterized by arthralgia (90% of the cases), fever, arthritis, rash, and, rarely, pneumonitis and cutaneous vasculitis . Patients also test positive for ANA and ANCA . To be diagnosed with MIL the patients must test positive for ANA, have no previous clinical history of lupus, and the situation must resolve when the causing drug is discontinued .

This medicine may cause an increased pressure in your head which can lead to permanent vision loss. Check with your doctor right away if you or your child has severe headache, blurred vision, or any vision changes. The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the minocycline, call your doctor. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

In the second follow-up visit, the patient continued with spironolactone and topical treatments. Akamin is an antibiotic that belongs to a group of medicines called tetracyclines. These medicines work by stopping the growth of bacteria which cause infections or make acne worse.

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